CYTOCHEMICAL ANALYSIS IN LEUKEMIA

Ultrastructural cytochemical analysis of blastic transformation of chronic myelocytic leukemia.

Ultrastructural cytochemical changes occurring during the blast phase of chronic myelocytic leukemia (CML) are described. Normal developing promyelocytes contain myeloperoxidase (MPO) -positive rough endoplasmic reticulum, nuclear envelope, and Golgi apparatus. All secretory granules of normal promyelocytes are also MPO-positive. In this study we have found abnormal promyelocytes with MPO-posit...

Cytochemical Study of Acute Leukemia in Special Relation to Children

Objectives: study of childhood leukemia among the Hospital attending Patients in Gauahati Medical Colleges and Hospital. Material and Method: The study was conducted in Gauhati Medical College and Hospital, Guwahati, Hospital in General Medicine Deptt., Deptt.of Hematology from March (2002-Feb 2003). (as per Medical Registration Deptt.) As per record 2002 total Hospital attending cases was 2,65...

Electron microscopic and peroxidase cytochemical analysis of pink pseudo-Chediak-Higashi granules in acute myelogenous leukemia.

Giant round pink inclusions (congruent to 2 micrometers) were seen in neutrophilic myeloblasts, promyelocytes, and myelocytes from three patients with acute myelogenous leukemia. On preliminary examination of the bone marrow smears, these inclusions looked like ingested red blood cells in that they were pink and not azurophilic. The bone marrow specimens were processed for the electron microsco...

Cytochemical and Haematological Studies in Leukemia Patients, Its Appraisal in Classification and Clinical Course of Leukemia

Hairy cell leukemia: a histo-cytochemical and ultra-structural study.

We studied five patients with hairy cell leukemia (HCL) diagnosed within the last ten years at the Department of Hematology of Universidade Federal de São Paulo-Escola Paulista de Medicina. Our purpose was to analyze the value of transmission electron microscopy (TEM) by comparing this method with the conventional ones. At diagnosis, patients presented weight loss, spleen enlargement and hairy ...